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The differences in AA sequences permitted development of quantitative assays for cTnI/T. Most cTn assays are non-aggressive enzyme-connected immunosorbent assays (ELISA) depending on the sandwich principle, utilizing the superior specificity and affinity of antibodies.31 The assay is predicated over a capture antibody which binds to a selected epit
Elucidation from the physiologically distinctive subunits of troponin in 1973 drastically facilitated our understanding of cardiac contraction. Despite the fact that troponins are expressed in equally skeletal and cardiac muscle mass, there are isoforms of troponin I/T expressed selectively in the heart. By exploiting cardiac-restricted epitopes in
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